Weight Loss Medications: Semaglutide vs Phentermine

When it comes to weight loss, there are various options available to help individuals achieve their goals. Two of the most popular medications for weight loss are Semaglutide and Phentermine.

Semaglutide, a newer medication, is primarily used for the treatment of diabetes, but was later discovered to be effective for weight loss and was FDA approved for that purpose. Semaglutide works by decreasing appetite and slowing the movement of food through the gastrointestinal tract, allowing individuals to feel full on less food. It is a GLP-1 medication and is considered more effective for weight loss compared to Phentermine. In studies, individuals lost an average of 15% of their body weight in one year with Semaglutide, compared to 5-10% with Phentermine.

Phentermine, on the other hand, is an older drug and a stimulant that works by decreasing appetite. The most common side effects of Phentermine include headaches, palpitations, sweating, and digestive issues such as diarrhea or constipation.

It is important to consider your medical history and lifestyle when deciding between these two medications. Semaglutide should be avoided by individuals with a history of thyroid cancer or
MEN Type 2, or if there is a family history of these conditions. It should also be used with caution if there is a history of pancreatitis, even though it has not been shown to cause that in studies, it is more of a theoretical risk. Phentermine should be avoided by individuals with glaucoma, uncontrolled hypertension, or significant cardiovascular disease such as recent coronary disease or stroke.



In terms of cost, Phentermine is generally more affordable, costing as low as $14 per month, compared to Semaglutide which can cost anywhere from $900 to $1,300 per month.
Both medications are approved for weight loss if an individual’s BMI is 30 or higher, or 27 if there are risk factors. If you have questions or are interested in using one of these medications,
please contact us.

In conclusion, both Semaglutide and Phentermine can be effective for weight loss, but it is important to consider your medical history and lifestyle, as well as the cost and potential side effects, when deciding which medication is right for you.